Figure 5. LTMRs and proprioceptive neurons are born primarily at E10.5.

(A) Representative images of EdU⁺ Ntrk2⁺ (detected by RNAscope) cells labeled at E10.5. (B) Representative images of EdU⁺ TRKC⁺ cells labeled at E10.5. (C, D) Quantitation of NF200⁺ (see Fig. 2), Ntrk2⁺, and TRKC⁺ neurons born at each time point as a percentage of all DRGs neurons (C) or all neurons of that subtype (D). Compared to nociceptors, these populations show a peak birth at E10.5. * indicates a significant increase in births from E9.5 to E10.5, # indicates a significant decrease in births from E10.5 to E11.5; see Supplemental Table 5 for all statistics.