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. 2021 Jul 8;31(9):965–979. doi: 10.1038/s41422-021-00532-7

Fig. 2. LD·ATTECs significantly reduced LDs in an autophagy-dependent manner.

Fig. 2

a Representative images and quantifications of OA-induced LDs in WT MEFs treated with the indicated compounds (n = 9, independently plated and treated wells; note that the DMSO group was the same for both the C1 and C2 plots). b Similar to a, but in Atg5–/– MEFs. c Similar to a, but in SH-SY5Y cells. Note that the DMSO group was the same for both the C1 and C2 plots. For all plots, bars indicate means ± SEM. The LD number per cell and averaged LD size in each cell were quantified by ImageJ (particle analysis) in a blinded manner. The replicate number indicates the number of independently plated wells. ns, P > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001; $P < 0.0001 by one-way ANOVA (the F and degree of freedom values have been indicated for each plot) and Dunnett’s post hoc tests (compared to the DMSO group).