Table 2.

Multivariable logistic regression for possible predictors of early neurological deterioration.

	Crude OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Model 1
Age	0.97 [0.94–1.01]	0.150	0.97 [0.93–1.01]	0.133
Sex	0.55 [0.25–1.21]	0.138	0.53 [0.20–1.36]	0.184
Initial NIHSS score	1.14 [1.07–1.21]	< 0.001	1.09 [1.01–1.17]	0.027
D-dimer*	1.80 [1.35–2.42]	< 0.001	1.45 [1.02–2.06]	0.040
Multiple territory lesion	2.58 [1.11–5.98]	0.027	1.03 [0.36–2.92]	0.963
Silent brain infarct	4.16 [1.84–9.40]	0.001	3.97 [1.53–10.33]	0.005
Model 2
Age	0.97 [0.94–1.01]	0.150	0.97 [0.93–1.01]	0.124
Sex	0.55 [0.25–1.21]	0.138	0.51 [0.19–1.34]	0.172
Initial NIHSS score	1.14 [1.07–1.21]	< 0.001	1.08 [1.01–1.17]	0.028
D-dimer*	1.80 [1.35–2.42]	< 0.001	1.45 [1.02–2.06]	0.040
Multiple territory lesion	2.58 [1.11–5.98]	0.027	1.02 [0.36–2.90]	0.976
Silent brain infarct		0.002		0.015
No	Ref	Ref	Ref	Ref
Single	3.45 [1.19–10.02]	0.023	3.05 [0.91–10.26]	0.071
Multiple	4.68 [1.88–11.64]	0.001	4.89 [1.60–14.94]	0.005

NIHSS = National Institutes of Health Stroke Scale.

*These variables were transformed using a log scale.