Table 3.
Baseline characteristics between favorable and unfavorable outcome groups.
| Favorable outcome (n = 80) |
Unfavorable outcome (n = 88) |
P value | |
|---|---|---|---|
| Age, y [IQR] | 68 [62–74] | 69 [61–74] | 0.990 |
| Sex, male, n (%) | 55 (68.8) | 47 (53.4) | 0.042 |
| Hypertension, n (%) | 38 (47.5) | 35 (39.8) | 0.313 |
| Diabetes, n (%) | 21 (26.2) | 29 (33.0) | 0.342 |
| Dyslipidemia, n (%) | 40 (50.0) | 31 (35.2) | 0.053 |
| Current smoking, n (%) | 29 (36.2) | 31 (35.2) | 0.890 |
| Cancer type, n (%) | < 0.001 | ||
| Lung | 27 (33.8) | 20 (22.7) | |
| Gastric/esophageal | 5 (6.2) | 12 (13.6) | |
| Colorectal | 5 (6.2) | 5 (5.7) | |
| Hepatobiliary | 13 (16.2) | 39 (44.3) | |
| Genitourinary | 22 (27.5) | 11 (12.5) | |
| Breast | 3 (3.8) | 1 (1.1) | |
| Others | 5 (6.2) | 0 (0) | |
| Systemic metastasis, n (%) | 32 (40.0) | 64 (72.7) | < 0.001 |
| Adenocarcinoma, n (%) | 33 (45.2) | 53 (71.6) | 0.001 |
| Initial NIHSS score [IQR] | 3 [1–5] | 9 [4–14] | < 0.001 |
| Thrombolytic therapy, n (%) | 1 (1.2) | 11 (12.5) | 0.005 |
| HbA1c, % [IQR] | 5.8 [5.5–6.3] | 6.1 [5.8–6.5] | 0.004 |
| Fasting glucose, mg/dL [IQR] | 99 [84–108] | 105 [91–117] | 0.022 |
| Total cholesterol, mg/dL [IQR] | 159 [138–205] | 171 [131–191] | 0.619 |
| White blood cell, × 103/µL [IQR] | 6.85 [5.67–9.65] | 8.01 [6.02–10.40] | 0.067 |
| High sensitivity CRP, mg/dL [IQR] | 0.50 [0.08–1.46] | 2.79 [0.90–9.04] | < 0.001 |
| D-dimer, µg/mL [IQR] | 0.97 [0.35–2.70] | 4.84 [1.57–18.02] | < 0.001 |
| MRI lesion pattern, (%) | < 0.001 | ||
| Single territory | 55 (68.8) | 26 (29.5) | |
| Multiple territory | 25 (31.2) | 62 (70.5) | |
| Periventricular WMH (Fazekas scale), [IQR] | 1 [1, 2] | 1 [0–2] | 0.103 |
| Subcortical WMH (Fazekas scale), [IQR] | 0 [0–1] | 0 [0–0] | 0.018 |
| Severe WMH, n (%) | 19 (23.8) | 16 (18.2) | 0.375 |
| Silent brain infarct, n (%) | 23 (28.8) | 40 (45.5) | 0.026 |
| Cerebral microbleeds, n (%) | 26 (32.5) | 15 (17.0) | 0.020 |
NIHSS = National Institutes of Health Stroke Scale, CRP = c-reactive protein, MRI = magnetic resonance imaging, WMH = white matter hyperintensity.