Table 2.
Univariate Cox regression exploring the relationship between different m5C regulatory gene expression levels and patient prognosis.
| Beta | HR | (95% CI for HR) | Wald test | P-value | CNV sig | |
|---|---|---|---|---|---|---|
| DNMT3A | − 0.31 | 0.74 | (0.57–0.95) | 5.6 | 0.018 | Yes |
| NSUN6 | − 0.3 | 0.74 | (0.57–0.96) | 5.2 | 0.022 | No |
| NSUN7 | − 0.21 | 0.81 | (0.64–1) | 3.2 | 0.071 | No |
| NSUN2 | 0.044 | 1 | (0.98–1.1) | 2.1 | 0.15 | Yes |
| NSUN3 | 0.21 | 1.2 | (0.76–2) | 0.71 | 0.4 | Yes |
| NSUN5 | 0.02 | 1 | (0.97–1.1) | 0.53 | 0.47 | No |
| NSUN4 | − 0.04 | 0.96 | (0.72–1.3) | 0.07 | 0.79 | Yes |
| TET2 | − 0.045 | 0.96 | (0.68–1.4) | 0.06 | 0.8 | Yes |
| ALYREF | − 0.0013 | 1 | (0.98–1) | 0.02 | 0.88 | Yes |
| DNMT3B | 0.031 | 1 | (0.69–1.5) | 0.02 | 0.88 | Yes |
| DNMT1 | − 0.0011 | 1 | (0.89–1.1) | 0 | 0.99 | Yes |