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. 2021 Apr 6;31(9):951–964. doi: 10.1038/s41422-021-00499-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Representative patch-clamp recordings of whole-cell currents elicited by glutamate in rat atrial cardiomyocytes. The holding potential was set at −60 mV. b Pooled data of the glutamate-elicited currents with different concentrations of glutamate. n = 9. c The AMPA or NMDA iGluR-gated currents in atrial cardiomyocytes were blocked by local application of CNQX or AP-5 in the perfusion solution at the holding potential of −60 mV. d Pooled data of the AMPA or NMDA iGluR-gated current densities from c. *P < 0.05, calculated by Student’s t-test, n = 9 per group.