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Kaplan-Meier survival curves for the effect of high-dose prenatal vitamin D3 supplementation on the development of asthma/recurrent wheeze at age 0–3 years stratified by mother and child 17q21 functional SNP rs12936231 genotype combinations in the VDAART and COPSAC2010 trials. G is considered as the dominant low-risk allele and C as the recessive high-risk allele. *P=0.005 in the Cox proportional hazard regression model.
