TABLE 1.
P‐values and Cohen's d of glycolytic genes that met the Bonferroni‐corrected α value and empirical P‐value cutoffs for significance in neurons, astrocytes, and oligodendrocytes, and microglia
| Glycolytic P‐values and Cohen's d‐values | ||||
|---|---|---|---|---|
| Dataset | Gene | P | Cohen's d‐value | |
| Neuron | MSBB parahippocampal gyrus | PFKL | 8.70 × 10‐13 | 1.515373 |
| MSBB superior temporal gyrus | PFKL | 5.91 × 10‐6 | 0.900013 | |
| Astrocyte | Mayo cerebellum | HK1 | 1.07 × 10‐14 | 1.554021 |
| IRS1 | 4.60 × 10‐15 | 1.581132 | ||
| SLC2A3 | 1.00 × 10‐14 | 1.556237 | ||
| Oligodendrocyte | Mayo temporal cortex | TPI1 | 5.48 × 10‐9 | 0.996358377 |
| MSBB frontal pole | TPI1 | .000716 | 0.621992169 | |
| PFKM | .000118 | 0.760133881 | ||
| PGAM1 | .00021 | 0.730112972 | ||
| MSBB inferior frontal gyrus | PKM | .000258 | 0.719315744 | |
| TPI1 | .000178 | 0.738811918 | ||
| ENO2 | 7.13 × 10‐12 | 1.441230355 | ||
| PFKM | 7.63 × 10‐10 | 1.27078558 | ||
| MSBB parahippocampal gyrus | PGAM1 | 3.02 × 10‐9 | 1.21863907 | |
| PGK1 | 5.89 × 10‐10 | 1.280517083 | ||
| PKM | 4.41 × 10‐9 | 1.204070491 | ||
| TPI1 | 5.19 × 10‐11 | 1.369950693 | ||
| ENO2 | .00017 | 0.738741297 | ||
| Microglia | MSBB superior temporal gyrus | GPI | .000386 | 0.695532656 |
| PFKM | .000154 | 0.743899193 | ||
| PKM | .000386 | 0.695485281 | ||
| Mayo cerebellum | HK1 | .001678 | 0.569799 | |
| PFKP | 2.80 x 10‐6 | 0.870544 | ||
| Mayo temporal cortex | SLC2A4 | .000261 | 0.602561 | |
| MSBB parahippocampal gyrus | ENO2 | 7.29 x 10‐5 | 0.785553 | |
Abbreviation: MSBB, Mount Sinai Brain Bank.