Table 2:

Summary of the included studies for systematic review

No.	First Author, (Yr)	Baseline disease reported	Community Health Workers program	Duration of intervention	Findings of physiological index
1	Tian et al (2015) (23 )	Hypertension, Coronary Heart Disease, Stroke, Diabetes	CHWs were instructed to provide monthly follow-up visits for the high-risk participants used mobile technology-based electronic decision support system (EDSS) (the Simplified Cardiovascular Manage-ment Study [SimCard]). The CHWs job desk was screening for new symptoms, diseases, and medication side effects, measuring blood pressure, providing life-style counseling, and, when appropriate, prescribing medications.	1 yr	Mean systolic blood pressure (SD); Intervention group: Pre 161.3 (29.6)mmHg, Post 149.5 (26.1) mmHg; Control group: Pre 161.4 (27.8)mmHg, Post 152.3(27.2) mmHg; Net difference=−2.7, P-value=0.04 Others outcome related NCDs prevention: Anti-hypertensive medication; Net difference= 25.5%, P-value=<0.001 Use of aspirin; Net difference=17.1%, P-value=<0.001
2	O’Neil et al (2016) (24 )	Hypertension, Asthma/COPD, Diabetes, Heart failure, Epilepsy	Chronic Disease in the Community program decentralized chronic disease care by transferring many clinical responsibilities to CHWs. Specially trained CHWs hold monthly meetings in their home villages in the presence of a clinician supervisor from a district hospital. At these meetings, the CHWs record a clinical evaluation of each patient using a disease-specific scripted examination. Thirty days of individually packaged medication from the district hospital supervisor are received on the day of the meeting and are delivered following the evaluation.	>6 months	Mean systolic blood pressure; Intervention group: 147.8 (144.3–151.3) mmHg; Control group: 156.7(153.2–156.7)mmHg, P-value=0.001
3	Margolius et al (2012) (25 )	Hypertension, Diabetes	Clinicians of patient completed an algorithm of antihypertensive medication adjustments. Health coaches (CHWs) made weekly telephone calls to participants to discuss overall well-being, adherence to action plans, and blood pressure values. Patients who reported systolic blood pressure greater than 140 mm Hg or diastolic blood pressure greater than 90 mm Hg and excellent medication adherence could choose to increase their antihypertensive medication regimen according to the algorithm without a clinician appointment.	6 months	Mean systolic blood pressure; Intervention group: Pre 160.3mmHg, Post 136.4mmHg; Control group:Pre 158.2mmHg, Post 136.4mmHg; Net difference=−4.6, P-value=not significant; Mean diastolic blood pressure, Intervention group: Pre 85.1mmHg, Post 79.2mmHg; Control group: Pre 86.9mmHg, Post 81.5mmHg; Net difference=−0.5, P-value=not significant
4	West et al (2011) (26 )	Obesity	Coaches (CHWs) reviewed the record of dietary intake and physical activity weekly. Then, returned it to the elderly with feed-back to reinforce behavior changes and identify targets for additional modification. Every week the elderly learns about behavioral strategies, self-monitoring, stimulus control, problem-solving, goal setting, and relapse prevention to support habit change. Group sessions duration about 60 minutes delivered by the CHWs.	4 months	Average weight loss, Intervention group reduced 3.7 kg compared with an average of 0.3 kg in the control arm. After adjusting for baseline weight, BMI, and gender, participants in the intervention arm had a 9.7 times higher odds (95%CI, 3.5–26.8) of achieving ≥5%weight reduction as compared to those in the control arm (P<.001 ).