Table 1. Implantation and viability rates for SCR and Slc38a2KD transduced embryos at E18.5.
SCR | Scl38a2KD | P-value | |
---|---|---|---|
Total embryos transferred (n) | 550 | 538 | |
Implanted (n) | 195 | 165 | |
% | 35% | 31% | 0.0941 |
Viable fetus at E18.5 | 178 | 113 | |
% | 32% | 21% | <0.0011 |
Number of fetuses per uterine horn (median, min-max) | 4 (0–9) | 2 (0–12) | <0.0012 |
Embryos were transferred to 58 recipient dams, of which 47 were pregnant, with any number of implantations, and 11 were non-pregnant at E18.5. SCR and Slc38a2 were compared by 1Fisher’s exact test or 2Mann–Whitney U-test.