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. 2021 Aug;10(8):2535–2545. doi: 10.21037/gs-21-505

Table 6. Relationship between EGFR and EZH2 expression and clinicopathological factors.

Clinical or pathological indicators N EGFR EHZ2
Relative expression P value Relative expression P value
Age (years) 0.199 0.645
   <40 21 0.537±0.280 0.582±0.346
   40–59 71 0.715±0.263 0.526±0.324
   ≥60 28 0.604±0.266 0.429±0.201
Menopausal state 0.962 0.494
   Not menopausal 65 0.651±0.280 0.478±0.290
   Menopausal 55 0.675±0.257 0.574±0.317
T stage 0.623 0.217
   T1 47 0.668±0.250 0.605±0.278
   T2 64 0.670±0.297 0.492±0.335
   T3 9 0.608±0.255 0.368±0.169
Lymph node 0.005* 0.024*
   N0 40 0.473±0.282 0.344±0.279
   N1 44 0.618±0.272 0.461±0.180
   N2 20 0.750±0.096 0.552±0.140
   N ≥3 16 0.865±0.099 0.721±0.313
Clinical stage 0.009* 0.013*
   I 25 0.361±0.221 0.243±0.226
   II 59 0.560±0.230 0.353±0.153
   III 36 0.768±0.123 0.724±0.317
Pathological grade 0.405 0.154
   I 15 0.816±0.040 0.769±0.371
   II 75 0.674±0.254 0.422±0.210
   III 30 0.592±0.318 0.610±0.373
Ki-67 0.203 0.046*
   <20% 36 0.566±0.257 0.380±0.269
   20–30% 32 0.661±0.297 0.516±0.310
   >30% 52 0.751±0.242 0.638±0.283
P53 0.770 0.538
   + 79 0.635±0.330 0.476±0.243
   − 41 0.574±0.334 0.419±0.327

*, indicates the result is statistically significant. EGFR, epidermal growth factor receptor; EZH2, zeste gene enhancer homolog 2.