Figure 2.

Silence of circRAD18 inhibits the proliferation and glucose metabolism of papillary thyroid cancer cells. (A) siRNA efficacy of circRAD18 was detected and assessed by qRT-PCR analysis. (B) Colony-formation assays revealed that knockdown of circRAD18 inhibited cell colony formatting ability. (C,D) After knockdown of circRAD18, the cell growth rate was evaluated by CCK-8 assays. (E) Glucose uptake rate was decreased after transfection with siRNA. (F) Lactate production rate was reduced after silencing of circRAD18. **, P<0.01.