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circRAD18 acts as a sponge of miR-516b in papillary thyroid cancer. (A) circRAD18, RAD18 mRNA, GAPDH, and 18S in different fractions. (B) Predicted binding sites of miR-516b within the circRAD18 sequence. (C) miR-516b expression was tested. (D) Dual luciferase reporter assay tested the interaction between miR-516b mimics and circRAD18 luciferase reporter. (E) RIP MS2-related assay was performed. **, P<0.01.
