Figure 5.

Effects of ZEB1 loss in astrocytes

(A) Representative images at 4 weeks post-induction, identifying SOX9⁺ SGZ astrocytes (insets).

(B) Representative images at 8 weeks post-induction, identifying S100β⁺ SGZ astrocytes (arrows).

(C) Quantification of SOX9⁺tdTOM⁺ non-RGL astrocytes in the SGZ (left) at 4 and 8 weeks post-induction and of S100β⁺tdTOM⁺ SGZ astrocytes (right) at 8 and 12 weeks post-induction.

(D) Quantification of SOX9⁺tdTOM⁺ (left) and S100β⁺tdTOM⁺ (right) astrocytes in the DG.

(E) Fraction of apoptotic GFAP⁺ RGL at 1 day post-induction.

(F) Fraction of SOX9⁺ apoptotic astrocytes at 4 weeks post-induction.

Dots represent individual mice (minimum of two sections analyzed per animal); numerical data are shown as mean ± SEM. Scale bars: 20 μm (insets: 10 μm).