REAGENT or RESOURCE	SOURCE	IDENTIFIER
Bacterial and virus strains
Mycobacterium ulcerans NCTC 10417	ATCC	Cat#ATCC 19432
Biological samples
Human skin swabs (Negative and positive for M. ulcerans)	Centre de Dépistage et de Traitement de l'Ulcère de Buruli, Pobè, Benin	https://ilepfederation.org/centre-de-depistage-et-de-traitement-de-la-lepre-et-de-lulcere-de-buruli-raoul-et-madeleine-follereau-de-pobe/
Human genomic DNA	Promega	Cat#G304A
Chemicals, peptides, and recombinant proteins
LbCas12a	NEB	Cat#M0653T
Recombinant Cas12a from Acidaminococcus sp. BV3L6	IDT	AsCas12a
Recombinant Cas13a from Leptotrichia buccalis, wild-type	East-Seletsky et al., 2017	LbuCas13a
Recombinant Cas13a from Leptotrichia buccalis, processing mutant K1082A	East-Seletsky et al., 2017	LbuCas13a K1082A
DNase I	NEB	Cat#M0303S
RNase A	IDT	Cat#11-02-01-02
Dynabeads™ MyOne™ Streptavidin C1	ThermoFisher	Cat#65002
Critical commercial assays
MagMAX™ Total Nucleic Acid Isolation Kit	ThermoFisher	Cat#AM1840
Qubit™ 1X dsDNA HS Assay Kit	ThermoFisher	Cat#Q33231
TaqMan Gene Expression Master Mix	Life Technologies	Cat# 4369106
Oligonucleotides
ssRNA oligos	Synthego	See Table S1
DNA oligos	IDT	See Table S1
IS2404	IDT	See Table S1
RNaseAlert Substrate	IDT	Cat#11-04-03-03
DNaseAlert Substrate	IDT	Cat#11-04-03-04
Software and algorithms
Prism 8	GraphPad	https://www.graphpad.com/
Excel	Microsoft	https://www.microsoft.com/