Table 1.
Clinical and Demographic Characteristics of the Deceased Live-Birth Infants: August 2018–March 2020, Karachi, Pakistan
| RSV Status | |||
|---|---|---|---|
| Variable | Negative, n (%) | Positive, n (%) | Total, n (%) |
| Total, n (%) | 363 (96.3) | 14 (3.7) | 377 (100.0) |
| Age at death | |||
| 0–3 months | 320 (88.2) | 12 (85.7) | 332 (88.1) |
| ≥3 months | 43 (11.8) | 2 (14.3) | 45 (11.9) |
| Age at death | |||
| Neonatal: 0–28 days | 250 (68.9) | 4 (28.6) | 254 (67.4) |
| Non-neonatal: ≥29 days | 113 (31.1) | 10 (71.4) | 123 (32.6) |
| Sex | |||
| Female | 146 (40.2) | 5 (35.7) | 151 (40.1) |
| Male | 217 (59.8) | 9 (64.3) | 226 (59.9) |
| Study site | |||
| Ali Akbar Shah Goth | 102 (28.1) | 10 (71.4) | 112 (29.7) |
| Bhains Colony | 107 (29.5) | 2 (14.3) | 109 (28.9) |
| Ibrahim Hyderi | 73 (20.1) | 2 (14.3) | 75 (19.9) |
| Rehri Goth | 81 (22.3) | 0 (0.0) | 81 (21.5) |
| Place of death | |||
| Community | 185 (51.0) | 4 (28.6) | 189 (50.1) |
| Hospital | 178 (49.0) | 10 (71.4) | 188 (49.9) |
| Symptom-based case definitions | |||
| Case | 194 (53.4) | 12 (85.7) | 206 (54.6) |
| Control | 169 (46.6) | 2 (14.3) | 171 (45.4) |
| Season of illness and death | |||
| Low (November to July) | 257 (70.8) | 5 (35.7) | 262 (69.5) |
| High (August to October) | 106 (29.2) | 9 (64.3) | 115 (30.5) |
| ALRI classificationa | |||
| ALRI | 84 (23.1) | 4 (28.6) | 88 (23.3) |
| Severe ALRI | 19 (5.2) | 3 (21.4) | 22 (5.8) |
| Very severe ALRI | 91 (25.1) | 5 (35.7) | 96 (25.5) |
| No respiratory symptoms | 169 (46.6) | 2 (14.3) | 171 (45.4) |
Abbreviations: ALRI, acute lower respiratory infection; RSV, respiratory syncytial virus.
aALRI, cough or difficulty breathing with increased respiratory rate for age; Severe ALRI, ALRI with wheeze and chest wall indrawing; Very severe ALRI, ALRI with at least 1 danger sign (eg, cyanosis, difficulty in breastfeeding or drinking, vomiting, convulsions, lethargy, unconsciousness, poor feeding, unconsciousness).