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. 2021 Sep 2;73(Suppl 3):S180–S186. doi: 10.1093/cid/ciab466

Table 2.

Associations With Respiratory Syncytial Virus (Adjusted and Unadjusted Risk Ratios)

Unadjusted Adjusted
Underlying Condition Risk Ratio (95% CI) P Risk Ratio (95% CI) P
Individual risk factors
 Prematurity or low birth weight .97 (.55, 1.72) .920 1.30 (.71, 2.37)a .393
 Complications of labor and delivery .89 (.47, 1.67) .716 1.08 (.56, 2.07)b .823
 Maternal HIV exposure 1.31 (.69, 2.49) .406 1.14 (.59, 2.17)b .701
 Congenital conditions (other) 1.03 (.47, 2.25) .942 .90 (.39, 2.08)b .805
 Hypoxic ischemic encephalopathy .65 (.24, 1.78) .405 .81 (.29, 2.27)b .695
 Congenital heart disease 4.04 (1.95, 8.34) <.001 3.57 (1.71, 7.44)a .001
 Malnutrition 1.56 (.51, 4.77) .434 .97 (.31, 3.07)b .964
 Genetic syndrome 1.49 (.22, 9.86) .680 1.30 (.20, 8.45)b .783
 Syphilis 1.64 (.25, 10.76) .607 1.80 (.28, 11.83)b .539
 No conditions identified .70 (.28, 1.73) .437 .64 (.26, 1.59)b .338
Combinations of related conditions
 Prematurity and/or complications associated with prematurity .66 (.35, 1.23) .189 .83 (.42, 1.62)b .583
 Prematurity and/or congenital heart disease 1.03 (.58, 1.85) .914 1.37 (.75, 2.51)a .311
 HIV and/or malnutrition 1.40 (.76, 2.58) .283 1.15 (.61, 2.16)b .668

Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus.

aAdjusted for age at death and place of birth.

bAdjusted for child gender, age at death, and place of birth.