Table 4. Associations Between Atopic Eczema Subtypes and Other Atopic Disease, General Health, and Mental Health in Midlife for the 1958 and 1970 Meta-analyses.
| Characteristic | OR (95% CI)a | SF-36 general health at age 46/50 y [n = 15 810], mean difference (95% CI) | |||
|---|---|---|---|---|---|
| Asthma (n = 17 200) | Rhinitis (n = 17 200) | Poor mental health at age 42 y (n = 17 978) | Poor general health at age 46/50 y (n = 18 733) | ||
| Atopic eczema | |||||
| Rare/no | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| High | 3.45 (2.82 to 4.21) | 2.70 (2.24 to 3.26) | 1.06 (0.85 to 1.32) | 1.26 (1.03 to 1.55) | −1.24 (−3.21 to 0.73) |
| Decreasing | 1.70 (1.38 to 2.10) | 1.42 (1.18 to 1.70) | 0.89 (0.73 to 1.08) | 0.88 (0.72 to 1.07) | 0.03 (−1.67 to 1.73) |
| Increasing | 2.11 (1.75 to 2.53) | 1.92 (1.64 to 2.25) | 1.45 (1.23 to 1.72) | 1.29 (1.09 to 1.53) | −4.52 (−6.12 to −2.92) |
| Atopic eczema | |||||
| Decreasing | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| High | 2.02 (1.53 to 2.68) | 1.91 (1.48 to 2.46) | 1.20 (0.90 to 1.61) | 1.44 (1.09 to 1.90) | −1.27 (−3.82 to 1.28) |
| Increasing | 1.24 (0.95 to 1.62) | 1.36 (1.07 to 1.72) | 1.64 (1.27 to 2.11) | 1.47 (1.15 to 1.89) | −4.55 (−6.83 to −2.27) |
| Atopic eczema | |||||
| Increasing | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| Decreasing | 0.81 (0.62 to 1.06) | 0.74 (0.58 to 0.93) | 0.61 (0.47 to 0.79) | 0.68 (0.53 to 0.87) | 4.55 (2.27 to 6.83) |
| High | 1.63 (1.26 to 2.12) | 1.41 (1.11 to 1.79) | 0.73 (0.56 to 0.96) | 0.98 (0.75 to 1.27) | 3.28 (0.79 to 5.77) |
Abbreviations: OR, odds ratio; SF-36, 36-Item Short Form Health Survey.
a
Each column represents a separate logistic or linear regression model predicting the odds of each health outcome. The rows show different reference groups for the same regression model.