Table 3.

Treatment effect estimates and Z-statistics for patients with the elevated d-dimer ($B-$) or non-elevated d-dimer ($B+$) and overall in the APEX trial.

Patient group	Elevated D-dimer $B-$	Non-elevated D-dimer $B+$	Full Population F
Events in treated patients	132/1914 (6.9%)	33/1198 (2.8%)	165/3112 (5.3%)
Events in control patients	166/1956 (8.5%)	67/1218 (5.5%)	223/3174 (7.0%)
Relative risk (95%CI)	0.81 (0.65, 1.00)	0.50 (0.33, 0.75)	0.76 (0.63, 0.92)
Log Relative Risk(Standard Error)	−0.21 (0.11)	−0.69 (0.21)	-0.28 (0.10)
Z-statistic	1.85	3.31	2.83