FIGURE 2.

Effects of supplementation with hyaluronan after hyaluronidase digestion in ex vivo. (a) Average flow speeds of perfusate from renal artery to renal vein. (b) Total urine volumes during perfusion. (c) Total urinary protein during perfusion. (d) Urinary protein every 10 min during perfusion. Proteinuria is significantly increased in the hyaluronidase‐treated group (c). Proteinuria is suppressed after supplementation with hyaluronan alone or hyaluronan and chondroitin sulfate (c, d). CS, chondroitin sulfate; HA, hyaluronan; Hya, hyaluronidase; n.s., not significant