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Regulation of immune system functions by p53 protein in tumor cells. The p53 protein is involved in the presentation of endogenous peptides through regulation of TAP1 and ERAP1. In addition, p53 regulates the expression of NKG2D ligands ULBP1 and ULBP2, as well as inhibition of expression PD-L1 ligand through miR-34 microRNA precursor family.
