Table II.

Omega fatty acid serum concentrations, presented with the mean ± SD, in fertile, subfertile and infertile women with age-adjusted fecundability ratios.

Omega fatty acid	Fertile pregnant 1–3 months (n = 50)	Subfertile pregnant 4–12 months (n = 100)	Infertile (n = 50)	P-value*	Age-adjusted fecundability ratio** (95% CI)
Omega-3
ALA	0.054 ± 0.045	0.043 ± 0.031	0.050 ± 0.043	0.201	0.98 (0.96, 1.01)
EPA	0.004 ± 0.003	0.005 ± 0.037	0.004 ± 0.029	0.363	0.88 (0.75, 1.03)
DHA	0.023 ± 0.014	0.025 ± 0.016	0.024 ± 0.012	0.829	0.95 (0.79, 1.14)
Omega-3 PUFAa	0.082 ± 0.056	0.073 ± 0.043	0.080 ± 0.53	0.507	0.99 (0.96, 1.01)
Long-chain omega-3 PUFAb	0.028 ± 0.017	0.030 ± 0.019	0.028 ± 0.015	0.737	0.97 (0.91, 1.04)
Omega-6
LA	0.595 ± 0.468	0.522 ± 0.371	0.605 ± 0.472	0.423	0.85 (0.66, 1.09)
DGLA	0.007 ± 0.004	0.007 ± 0.004	0.007 ± 0.003	0.958	1.01 (0.73, 1.40)
AA	0.046 ± 0.018	0.048 ± 0.018	0.048 ± 0.015	0.798	0.97 (0.91, 1.03)
Omega-6 PUFAc	0.648 ± 0.486	0.577 ± 0.386	0.671 ± 0.484	0.402	0.86 (0.69, 1.09)
Ratio of omega-6 to omega-3	8.075 ± 2.283	7.86 ± 2.068	8.500 ± 2.620	0.277	1.01 (0.97, 1.06)
Ratio of LA to ALA	12.122 ± 3.246	13.125 ± 4.395	12.816 ± 3.812	0.348	1.04 (0.79, 1.36)
Total PUFA	0.730 ± 0.538	0.650 ± 0.426	0.751 ± 0.533	0.411	0.87 (0.71, 1.08)

^*ANOVA.

^**For LA, Omega-6 PUFA and Total PUFA the fecundability ratio is for a 1 μmol/ml increase in concentration. All other omega fatty acid variables were multiplied by 100 and therefore the fecundability ratio represents a 1/100 μmol/ml change in concentration.

^aaSum of ALA, EPA, DHA.

^bbSum of EPA, DHA.

^ccSum of LA, DGLA, AA.

AA, arachidonic acid; ALA, alpha linolenic acid; ANOVA, analysis of variance; CI, confidence interval; DGLA, dihommo-gamma linolenic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; LA, linoleic acid; PUFA, polyunsaturated fatty acids.

Because of using inverse probability weighting, the 95% CIs were calculated using robust variance.