Table 2. Inflammatory parameters in the 40 male participants.
| Experimental conditions | Control | |||||||
|---|---|---|---|---|---|---|---|---|
| Hypoxia baseline (n=10) | Hypoxia peak (n=10) | LPS baseline (n=10) | LPS peak (n=10) | LPS+hypoxia baseline (n=10) | LPS+hypoxia peak (n=10) | Baseline (n=10) | Peak (n=10) | |
| Leukocytes, ×109/l | 5.5 ± 1.2 | 7.8 ± 1.4 | 4.9 ±1.1 | 11.0 ± 1.9 | 5.2 ± 1.1 | 14.5 ± 1.6 | 6.2 ± 1.6 | 6.2 ± 1.3 |
| Body temperature, °C | 36.4 ± 0.3 | 36.6 ± 0.4 | 36.6 ± 0.3 | 37.9 ± 0.6 | 36.8 ± 0.3 | 38.3 ± 0.6 | 36.7 ± 0.4 | 37.0 ± 0.4 |
| Plasma TNF-α, pg/mL | 5.5 ± 2.9 | 5.0 ± 2.7 | 3.8 ± 0.7 | 284.6 ± 135.1 | 3.9 ± 0.9 | 195.5 ± 77.0 | 4.6 ± 1.9 | 4.1 ± 1.7 |
| Plasma IL-6, pg/ml | 3.2 ± 0.0 | 3.2 ± 0.0 | 3.2 ± 0.0 | 478.6 ± 241.3 | 3.2 ± 0.0 | 292.3 ± 156.4 | 1.9 ± 0.4 | 1.8 ± 0.1 |
Data are means ± standard deviation.
LPS, lipopolysaccharide
Peak was measured at 360, 180, 90 and 120 min post-LPS administration for leukocytes, body temperature, TNF-α and IL-6, respectively.