Table 3.

MR Results for MPV and PLT

Trait	Protein	Number of SNPs	β†	SE	p-value‡
MPV	GP5*	1	−0.112	0.0250	7.57E-06
	MPO	6	0.0407	0.0102	6.57E-05
	CD5L	4	−0.0350	0.00934	1.76E-04
	GRN*	2	−0.183	0.0522	4.63E-04
PLT	GRN*	2	0.148	0.0146	4.38E-24
	MCAM	1	−0.259	0.0289	3.09E-19
	GP5*	1	0.0988	0.0252	9.05E-05
	SERPINA10	28	0.0141	0.00369	1.31E-04

^*Proteins showing significant causal association with both MPV and PLT.

^†Units: per standard deviation increment of rank-based inverse normal transformed protein level

^‡Bonferroni Corrected Significance Threshold P = 0.05/37 = 1.35E-03