Recommendations
1. | IgG4-SC is an uncommon cause for cholestatic jaundice, and should be considered in patients with AIP and other IgG4-related disorders and cholestasis. (Grade II-2/B) |
2. | The diagnosis of IgG4-SC is based on several criteria including elevated IgG4, cholangiographic findings, and AIP or other IgG4 related diseases. (Grade II -2/B) |
3. | PSC and CC should be considered and ruled out in patients with IgG4-SC. (Grade II-3/C) |
4. | Prednisolone is the treatment of choice for patients with IgG4-SC with excellent outcomes in majority of patients. (Grade II-2/A) |
5. | Consider re-induction with prednisolone therapy in IgG4-SC for disease recurrence after withdrawal of maintenance treatment. (Grade II-3/B) |
6. | Endoscopic dilatation and stenting are required for IgG4-SC patients with evidence of biliary obstruction. (Grade II-3/B) |