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. 2021 Jul 27;27(Suppl 1):S1–S26. doi: 10.4103/sjg.sjg_112_21

Recommendations

1. IgG4-SC is an uncommon cause for cholestatic jaundice, and should be considered in patients with AIP and other IgG4-related disorders and cholestasis. (Grade II-2/B)
2. The diagnosis of IgG4-SC is based on several criteria including elevated IgG4, cholangiographic findings, and AIP or other IgG4 related diseases. (Grade II -2/B)
3. PSC and CC should be considered and ruled out in patients with IgG4-SC. (Grade II-3/C)
4. Prednisolone is the treatment of choice for patients with IgG4-SC with excellent outcomes in majority of patients. (Grade II-2/A)
5. Consider re-induction with prednisolone therapy in IgG4-SC for disease recurrence after withdrawal of maintenance treatment. (Grade II-3/B)
6. Endoscopic dilatation and stenting are required for IgG4-SC patients with evidence of biliary obstruction. (Grade II-3/B)