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. 2021 Jul 27;27(Suppl 1):S1–S26. doi: 10.4103/sjg.sjg_112_21

Recommendations

1. MRCP is the preferred investigation technique for the diagnosis of PSC in patients with cholestatic biochemical profile over endoscopic ERCP. (Grade I/A)
2. In patients with typical cholangiographic findings for PSC, liver biopsy is not indicated. (Grade I/B)
3. Liver biopsy is recommended to diagnose cases of small duct PSC or to exclude other conditions such as suspected autoimmune hepatitis overlap. (Grade I/B)
4. Screening for varices in patients with signs of advanced disease and platelet counts of <150 × 103/dL is recommended. (Grade II-1/B)