Recommendations
1. | MRCP is the preferred investigation technique for the diagnosis of PSC in patients with cholestatic biochemical profile over endoscopic ERCP. (Grade I/A) |
2. | In patients with typical cholangiographic findings for PSC, liver biopsy is not indicated. (Grade I/B) |
3. | Liver biopsy is recommended to diagnose cases of small duct PSC or to exclude other conditions such as suspected autoimmune hepatitis overlap. (Grade I/B) |
4. | Screening for varices in patients with signs of advanced disease and platelet counts of <150 × 103/dL is recommended. (Grade II-1/B) |