Figure 3.

Anti-inflammatory role of NIM in reducing the progression of IMQ induced psoriasis like inflammation. (a-f) ELISA and Griess assay analysis for determining expression of various inflammatory cytokines including IL-6, IL-1β, TGF-β1, IL-22, IL-17 and NO respectively. ^****P< 0.0001, ^**P< 0.01, *P< 0.05 of IMQ versus Normal Control; ^{^^^^}P< 0.0001, ^{^^^}P< 0.001,^{^^}P< 0.01, ^{^}P< 0.05 of NIM versus IMQ. TGF = Transforming growth factor, IMQ = Imiquimod, NIM = Nimbolide, IL = Interleukin, NO = Nitric oxide