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. 2021 May 27;31(3):e12962. doi: 10.1111/bpa.12962

TABLE 4.

Inflammatory features in SLONM

SLONM SLONM‐noMGUS SLONM‐MGUS SLONM‐HIV
(total = 49) (n = 34) (n = 13) (n = 2)
Immunohistochemistry
MHCn, regenerating fibers (%) 5.8 ± 9.3a 5.1 ± 9.9b 9.0 ± 7.9c 0.65 ± 0.5
≤1% 16 [36.4]a 13 [39.4]b 3 [27.3]c 2 [100.0]
>1 to ≤5% 15 [34.1]a 14 [42.4]b 1 [9.1]c 0
>5 to ≤10% 5 [11.4]a 2 [6.1]b 3 [27.3]c 0
>10% 8 [18.2]a 4 [12.1]b 4 [36.4]c 0
CD3 in 10 HPF 19.4 ± 27.7b 19.0 ± 30.6 19.3 ± 20.5b 28.0 ± 22.6
CD8 in 10 HPF 17.9 ± 26.4b 18.0 ± 29.8 17.8 ± 17.0b 18.0 ± 17.0
CD20 in 10HPF 2.1 ± 4.6c 1.7 ± 3.7 3.2 ± 6.8c 0
CD68 in 10HPF 99.9 ± 94.3b 105.1 ± 104.8 89.0 ± 63.4b 78.0 ± 87.7
HLA‐ABC 32 [66.7]b 23 [67.6] 8 [66.7]b 1 [50.0]
Score 1 10 [20.8]b 5 [14.7] 5 [41.7]b 0
Score 2 13 [27.1]b 9 [26.5] 3 [25.0]b 1 [50.0]
Score 3 9 [18.8]b 9 [26.5] 0b 0
HLA‐DR 1 [2.1]b 0 1 [8.3]b 0
MAC capillary deposition 29 [60.4]b 21 [61.8] 6 [50.0]b 2 [100]
Score 1 19 [39.6]b 11 [32.4] 6 [50.0] b 2 [100]
Score 2 8 [16.7]b 8 [23.5] 0b 0
Score 3 2 [4.2]b 2 [5.9] 0b 0
MAC sarcolemmal deposition 6 [12.5]b 5 [14.7] 1 [8.3]b 0
Score 1 2 [4.2]b 2 [5.9] 0b 0
Score 2 3 [6.3]b 2 [5.9] 1 [8.3]b 0
Score 3 1 [2.1]b 1 [2.9] 0b 0
MAC capillary/sarcolemmal deposition, mixed 9 [18.8]b 7 [20.6] 2 [16.7]b 0
p62 (fine granular pattern) 36 [78.3]a 26 [78.8]b 8 [72.7]c 2 [100]
Score 1 6 [13.0]a 4 [12.1]b 2 [18.2]c 0
Score 2 12 [26.1]a 10 [30.3]b 2 [18.2]c 0
Score 3 18 [39.1]a 12 [36.4]b 4 [36.4]c 2 [100]

Abbreviations: CD, cluster of differentiation; HLA‐ABC, human leukocyte antigen‐ABC; HLA‐DR, human leukocyte antigen‐DR; HPF, high power field (40x objective); MAC, membrane attack complex (C5b‐9); MHCn, neonatal myosin; p62 (STQM1); SLONM‐HIV, SLONM associated with HIV; SLONM‐MGUS, SLONM with MGUS association; SLONM‐noMGUS, SLONM without MGUS association.

a

Information not available in three cases.

b

Information not available in one case.

c

Information not available in two cases.