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. Author manuscript; available in PMC: 2021 Sep 2.
Published in final edited form as: Curr Behav Neurosci Rep. 2019 Jan 17;6(1):1–11. doi: 10.1007/s40473-019-0170-4

Figure 1 -.

Figure 1 -

Summary of fMRI findings from drug cue reactivity studies in opioid-use disorder

Individuals with opioid-use disorder exhibit heightened brain responses to drug cues. These are reduced with medication assisted treatments and following prolonged abstinence. Based on data reviewed in: Moningka H, Lichenstein S, Worhunsky PD, DeVito EE, Scheinost D, & Yip SW. Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research. Neuropsychopharmacology, 2018.

Abbreviations: OFC, orbitofrontal cortex; THA, thalamus; ACC, anterior cingulate cortex; HIP, hippocampus; MBN, midbrain; AMY, amygdala; INS, insula; STR, striatum; IFG, inferior frontal gyrus.