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. 2021 Sep 2;413(26):6457–6468. doi: 10.1007/s00216-021-03628-6

Fig. 1.

Fig. 1

Characterization of CDNs by LC-MS/MS. a Extracted ion chromatograms (EIC) of CDN standards at concentration 100 nmol/L analyzed by LC-MS (full scan). Tandem mass spectra of 2′3′ cGAMP (b), 3′3′ cGAMP (c), c-di AMP (d), and c-di-GMP (e), using 30 V CE. Fragments used for the LC-MS/MS quantification are highlighted in red. The proposed fragments are designated as neutral molecules