FIG. 8.

Loss of Ume3p activity suppresses the hypersensitivity of plc1 mutants to hyperthermia and oxidative stress. (A) Suppression of growth defects in plc1 mutants. Isogenic strains with the indicated genotypes were streaked onto rich medium and plated at 30°C or 37°C or were grown at 30°C in the presence of 0.8 mM H₂O₂. The cells were incubated for 2 days and photographed. (B) Suppression of cell morphology defects in plc1 mutants. Cells obtained from the 37°C plate shown in panel A were examined with Numarski optics at a 400× final magnification. The genotypes are listed below each image.