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. Author manuscript; available in PMC: 2021 Sep 2.
Published in final edited form as: J Am Coll Cardiol. 2017 Sep 26;70(13):1587–1597. doi: 10.1016/j.jacc.2017.07.775

CENTRAL ILLUSTRATION. Use of IVC Filters Compared With Controls.

CENTRAL ILLUSTRATION

In this review and analysis of studies of IVC filters versus none in patients at risk of PE, the results were limited by the small number of patients (total N = 4,204 patients, but fewer for some outcomes), methodological limitations with the included studies, and clinical heterogeneity across the studies. Summary results suggested that for every 100 patients, there would be 5 fewer subsequent PEs, 2 excess DVTs, and no change in all-cause mortality. The results appeared more favorable in limited scenarios that resembled guidelines indications, although no randomized trials existed. DVT = deep vein thrombosis; IVC = inferior vena cava; PE = pulmonary embolism.