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SHK benefit is inversely proportional to eGFR in a multivariable Cox regression analysis. Marginal effect of SHK on hazard of death across values of eGFR in (a) unadjusted model and (b) adjusted model. The line plotted is the median of simulations performed to obtain marginal effects with the inner darker band the 50% CI and outer lighter band the 95% CI. The rug represents the distribution of values used to perform the underlying Cox regression.
