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. 2021 Sep 3;9:43. doi: 10.1186/s40635-021-00406-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Comparison of progranulin (PGRN, A) and procalcitonin (PCT, B) plasma concentrations in healthy volunteers, patients with SIRS and patients with either sepsis or septic shock ("Sepsis") at study inclusion. Data are presented separately for the exploratory (blue boxplots) and the confirmatory study (orange boxplots). *Indicates a p < 0.001, significant p values ≥ 0.001 are given as numbers