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Hemolytic activity of A22 alone and in combination with conventional antibiotics toward human erythrocytes.
| Treatment | Concentration (μg/mL) | Mean hemolytic activity (%) ± SD |
|---|---|---|
| A22 hydrochloride | 256 | 0.9 ± 0.4 |
| 2–128 | 0 | |
| Azithromycin | 2–256 | 0 |
| Cefoxitin | ||
| Ceftazidime | ||
| Ciprofloxacin | ||
| Gentamicin | ||
| Meropenem | ||
| A22+ azithromycin | 128 + 128 | 0 |
| A22+ cefoxitin | ||
| A22+ ceftazidime | ||
| A22+ ciprofloxacin | ||
| A22+ gentamicin | ||
| A22+ meropenem |
