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. 2021 May 3;58(10):1351–1358. doi: 10.1007/s00592-021-01721-x

Table 1.

Baseline clinical and diabetic foot ulcers’ characteristics of all sample, early reffereral and late referral groups

Variables All sample (n = 200) Early referral (n = 159) Late referral (n = 41) P
Age (years) 70 ± 13 71 ± 13 66 ± 13 0.03
Sex (male) (n) (%) 125 (62.5) 98 (61.6) 27 (63.4) 0.7
Diabetes (type 2) (n) (%) 182 (91) 149 (93.7) 33 (80.5) 0.04
Diabetes duration (years) 18 ± 11 17 ± 8 23 ± 17 0.003
HbA1c (mmol/mol) (%) 60 ± 10 (7.6 ± 3.3) 58 ± 9 (7.5 ± 3.2) 62 ± 18 (7.8 ± 3.8) 0.08
ESRD (n) (%) 25 (12.5) 14 (8.8) 11 (26.8%) 0.004
IHD (n) (%) 78 (39) 58 (36.5) 20 (48.8) 0.1
Hypertension (n) (%) 193 (96.5) 154 (96.9) 39 (95.1) 0.6
Dyslipidemia (n) (%) 158 (79) 120 (70.5) 38 (92.7) 0.008
COPD (n) (%) 26 (13) 19 (11.9) 7 (17.1) 0.4
CVD (n) (%) 36 (18) 28 (17.6) 8 (19.5%) 0.7
Ulcer severity
Uncomplicated DFU (10.5) 21 (13.2) 0 (0)  < 0.0001
Complicated DFU (61.5) 106 (66.7) 17 (41.5)
Severely complicated (28) 32 (20.1) 24 (58.5)
Ischaemia 111 (55.5) 80 (50.3) 31 (75.6) 0.002
Infection 135 (67.5) 103 (64.8) 32 (78) 0.07
Deep to the bone 119 (61) 88 (55.3) 31 (75.6) 0.009
Dimension (> 5 cm2) 127 (63.5) 91 (57.2) 36 (90) 0.003
Gangrene 85 (42.5) 52 (37.7) 33 (80.5)  < 0.0001

HbA1c hemoglobin A1c; ESRD end-stage-renal-disease; IHD ischaemic heart disease; COPD chronic obstructive pulmonary disease; CVD cerebrovascular disease; DFU diabetic foot ulcer