Table 1.
Characteristics of the amyloid-PET positive study cohort.
| Variable | N | Summary measures* |
|---|---|---|
| Age (years) | 598 | 73.6 (7.0) |
| Education (years) | 596 | 16.1 (2.7) |
| Sex (female) (%) | 598 | 302 (50.5%) |
| APOE4 (%) | 598 | 376 (62.9%) |
| Aβ42 (pg/ml) | 596 | 748.9 (307.4) |
| Aβ40 (pg/ml) | 130 | 18,641.7 (5479.9) |
| p-tau (pg/ml) | 596 | 33.3 (15.3) |
| t-tau (pg/ml) | 597 | 335.6 (138.5) |
| ADNI-MEM (z-score) | 597 | 0.1 (0.9) |
| ADNI-EF (z-score) | 593 | 0.0 (1.1) |
| Amyloid PET (SUVR) | 598 | 1.39 (0.18) |
| Amyloid PET (CL) | 598 | 76.4 (34.7) |
| L hippocampus (mm3) | 493 | 3307.9 (561.5) |
| R hippocampus (mm3) | 493 | 3385.8 (582.7) |
| B hippocampi (mm3) | 493 | 3346.8 (552.2) |
*Data are expressed in mean (standard deviation) or frequency (%). ADNI: Alzheimer's Disease Neuroimaging Initiative; ADNI-MEM: ADNI memory score; ADNI-EF: ADNI executive function score; APOE4: APOE ε4 allele; Aβ42: 42-amino acid β amyloid peptide; Aβ40: 40-amino acid β amyloid peptide; CL: centiloid; p-tau: phopsho-Tau; t-tau: total-Tau; pg: picogram; ml: milliliters; PET: Positron Emission Tomography; SUVR: standard uptake value ratio; L: left; R: right; B: average bilateral volume.; mm: millimeters.