Table 4.

The prognosis models and the corresponding predictors for ADAS-13 (N = 110) and MMSE (N = 92) predictive dataset.

Prognosis models	Predictors
Baseline
A1/M1	Age, gender, marital status, ApoEε4, ADAS-13_bl, MMSE_bl, and CDRSB_bl
A1+ baseline MRI/M1+ baseline MRI	A1/M1+ Hippocampus_bl, WholeBrain_bl, and Entorhinal_bl
Longitudinal
A2/M2	Age, gender, marital status, ApoEε4, ADAS-13_bl, MMSE_bl, CDRSB_bl, $\mathrm{\Delta }$ADAS-13, $\mathrm{\Delta }$MMSE, and $\mathrm{\Delta }$CDRSB
A2+ baseline MRI/M2+ baseline MRI	A2/M2+ Hippocampus_bl, WholeBrain_bl, and Entorhinal_blc
A2+ ∆MRI/M2+ ∆MRI	A2/M2+ $\mathrm{\Delta }$Hippocampus, $\mathrm{\Delta }$WholeBrain, and $\mathrm{\Delta }$Entorhinal

A1, ADAS-13 baseline Prognosis Model; A2, ADAS-13 longitudinal Prognosis Model; M1, MMSE baseline Prognosis Model; M2, MMSE longitudinal Prognosis Model; ADAS-13_bl, Alzheimer Disease Assessment Scale Cognitive 13 items at Baseline; MMSE_bl, Mini mental state examination at Baseline; CDRSB_bl, Clinical Dementia Rating Sum of Boxes at Baseline; Hippocampus_bl, The Total Volumes of The Hippocampus at Baseline; WholeBrain_bl, Whole Brain at Baseline; Entorhinal_bl, Entorhinal Cortex at Baseline; ∆ADAS-13, (ADAS-13_M12 − ADAS-13_bl)/1 year; ∆MMSE, (MMSE_M12 − MMSE_bl)/1 year; ∆CDRSB, (CDRSB_M12 − CDRSB_bl)/1 year; ∆Hippocampus, (Hippocampus _M12 − Hippocampus _bl)/1 year; ∆WholeBrain, (WholeBrain _M12 − WholeBrain _bl)/1 year; ∆Entorhinal, (Entorhinal _M12 − Entorhinal _bl)/1 year.