Table 8.
Comparison of physicochemical and solubility properties of different vaccine constructs.
| Physicochemical properties | Vaccine 1 | Vaccine 2 | Vaccine 3 |
|---|---|---|---|
| Antigenic propensity | 1.062 | 0.83 | 0.992 |
| Solubility | 0.651 | 0.601 | 0.472 |
| Molecular weight | 42.3 kDa | 50.70 kDa | 54.7 kDa |
| Allergenicity | Non-allergenic | Non-allergenic | Non allergenic |
| Hydropathicity | − 0.062 | − 0.056 | − 0.14 |
| Amino acids | 406 | 485 | 520 |
| Theoretical isoelectric point (pI) | 9.7 | 9.45 | 9.05 |
| Aliphatic index | 78.37 | 89.94 | 83.23 |
| Instability index (II) | 30.95 | 27.71 | 32.94 |