Fig. 1.

Hypothesis 1 examining T1 MDD severity predicting T3 EF via T2 inflammation.

Note: ***p < .001; **p < .01; *p < .05. λ, factor loading; ϵ, item error variance; ζ, residual error variance; BC, backward counting; BDS, digit backward span; CFI, confirmatory fit index; CRP, C-reactive protein; d = Cohen’s d effect size; IL-6, interleukin-6; RMSEA, root mean square error of approximation; SGST, stop-and-go-switch task mixed task; SX, symptom severity; T1, time 1; T2, time 2; T3, time 3; VF, verbal fluency.