Table 3.
Virtual non-calcium computed tomography potential to visualize non-traumatic bone marrow edema on dual-energy scans of spine and pelvic girdle
| Authors, year [reference] | DECT platform | Number of patients | Qualitative analysis (sensitivity, specificity, accuracy) | Quantitative analysis cutoff (sensitivity, specificity, accuracy) | Reference standard | Disorder | Anatomical site |
|---|---|---|---|---|---|---|---|
| Shinohara et al., 2020 [61] | DSCT | 53 | NA | NA | MRI | Disc degeneration | Spine |
| Foti et al., 2020 [74] | DSCT | 59 | 95%, 86%, 93% | NA | MRI | Sacroiliitis | Hip |
| Chen et al., 2020 [71] | DSCT | 40 | 81%, 94%, NA | -44 HU (76%, 91%, NA) | MRI | Sacroiliitis | Hip |
| Gruggeberger et al., 2020 [73] | DSCT | 47 | 93%, 94%, NA | -35 HU (94%, 83%, NA) | MRI | Sacroiliitis | Hip |
| Abdullayev et al., 2019 [56] | DLCT | 21 | 85%, 84%, 84% | NA | MRI | Vertebral metastases | Spine |
| Booz et al., 2019 [34] | DSCT | 41 | 91%, 92%, 94% | NA | MRI | Disc herniation | Spine |
| Wu et al., 2019 [70] | DSCT | 47 | 93%, 94%, 92% | -33 HU (90%, 83%, 83%) | MRI | Sacroiliitis Spondylarthritis | Spine/Hip |
| Kosmala et al., 2018 [12] | DSCT | 53 | NA | -36 HU (100%, 97%, 99%) | MRI | Multiple myeloma | Spine |
| Kosmala et al., 2018 [66] | DSCT | 34 | 91%, 91%, 91% | -45 HU (93%, 92%, 93%) | MRI | Multiple Myeloma | Spine |
DECT Dual-energy computed tomography, DLCT Dual-layer computed tomography, DSCT Dual-source computed tomography, HU Hounsfield units, NA Not available, MRI Magnetic resonance imaging