Table 4.
Virtual non-calcium computed tomography ability to depict traumatic bone marrow edema on dual-energy scans of appendicular skeleton
| Author | DECT platform | Number of patients | Qualitative analysis (sensitivity, specificity, accuracy) | Quantitative analysis cutoff (sensitivity, specificity, accuracy) | Reference standard | Anatomical site |
|---|---|---|---|---|---|---|
| Yang et al., 2020 [81] | DSCT | 156 | 92%, 93%, 93% | NA | MRI | Knee |
| Booz et al., 2020 [82] | DSCT | 56 | 96%, 97%, 97% | -51 HU* (96%, 97%, 96%) | MRI | Knee |
| Yadav et al., 2020 [83] | DSCT | 40 | 94%, 91%, 92% | NA | MRI | Lower limb |
| Wang et al, 2019 [80] | DSCT | 35 | 88%, 98%, 95% | -67 HU (81%, 99%, 90%) | MRI | Knee |
| Booz et al., 2019 [85] | DSCT | 62 | 92%, 97%, 98% | -53 HU (82%, 95%, 98%) | MRI | Calcaneus |
| Foti et al., 2019 [87] | DSCT | 40 | 92%, 86%, 90% | -20 HU (88%, 92%, 87%) | MRI | Ankle |
| Jang et al., 2019 [36] | DSCT | 35 | 100%, 100%, 100% | -55 HU (100%, 94%, 95%) | Standard CT | Hip |
| Ali et al., 2018 [86] | DSCT | 24 | NA | 6 HU (100%, 99%, 100%) | Visual assessment | Wrist |
| Kellock et al., 2017 [37] | DSCT | 118 | 100%, 100%, NA | NA | Clinical follow-up | Hip |
| Reddy et al., 2015 [69] | DSCT | 25 | 90%, 40%, NA | NA | Clinical follow-up | Hip |
| Guggenberger et al., 2012 [47] | DSCT | 30 | 90%, 81%, 97% | NA | MRI | Ankle |
BME Bone marrow edema, CT Computed tomography, DECT Dual-energy computed tomography, DSCT Dual-source computed tomography, HU Hounsfield units; NA Not available, MRI Magnetic resonance imaging. *Cutoff value refers to tibial BME