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. 2021 Jun 24;22:401–414. doi: 10.1016/j.omtm.2021.06.010

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© 2021 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Correlation of CAPN3 expression levels with treadmill performance

(A) Scattergram showing a correlation between the total mRNA levels from four representative muscles (TA, gastrocnemius, quadriceps, and triceps) from the old age group correlating with the run-to-exhaustion test in the LD (3 × 10¹² vg, n = 12) cohort (R² = 0.5192, p = 0.0082, linear regression analysis). In the HD cohort (6 × 10¹² vg, n = 12), no correlation was seen between mRNA levels and run-to-exhaustion test performance. (B) The mRNA level window for the best treadmill performance favored females from the HD and LD cohorts.