Figure 2.

LINC00941 depletion suppresses the growth of PDAC cancer cells

(A) LINC00941 expression in human pancreatic duct epithelial (HPDE) and PDAC cancer cell lines. (B) Knockdown efficiency in PANC-1 and SW1990 cells. (C and D) Cell viability assay of PDAC cell lines silenced with LINC00941 or overexpressed with LINC00941. (E) Represented results of the colony formation in LINC00941 control and knockdown cell lines. (F) Represented results of the 3D-on-top growth in LINC00941 control and knockdown cell lines. All statistical significances were calculated using two-tailed Student’s t tests to compare with the NC or control group. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.