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. 2021 Jul 16;26:280–294. doi: 10.1016/j.omtn.2021.07.004

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Growth-promoting effects of LINC00941 to PDAC cells depend on the enhanced glycolysis

(A) Cell viability assay of PDAC cell lines with LINC00941 overexpression and 2-DG treatment or not. (B) Glucose uptake of PDAC cell lines with LINC00941 overexpression and 2-DG treatment or not. (C) Cell viability assay of PDAC cell lines with indicated treatment cultured in medium in which galactose replaced glucose. (D) Lactate production of PDAC cell lines with indicated treatment cultured in medium in which galactose replaced glucose. (E) Representative PET-CT results of high and low LINC00941 expression of PDAC patients. (F) The SUVmax statistical results of PDAC patients. (G) IHC staining of high and low LINC00941 expression of PDAC specimens. All statistical significances were calculated using two-tailed Student’s t tests to compare with the NC or control group. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.