TABLE 3.
Gender | AOO (years) | SOO | FTD | Duration (months) | Family history | Ethnicity | Reference | |
---|---|---|---|---|---|---|---|---|
1 patient | F | 59 | UL | No | — | Yes | Caucasian | (Rutherford et al., 2008) |
3 patients | M | 66 | B | No | 42 | Yes | Caucasian | (Ticozzi et al., 2011) |
M | 25 | LL | No | — | Yes | Caucasian | ||
F | 57 | UL | No | 50 | Yes | Caucasian | ||
2 patients | F | 59 | LL | No | >103 | No | Dutch | (van Blitterswijk et al., 2012) |
M | 46 | LL | No | 64 | Yes | Dutch | ||
1 patient | — | — | — | No | — | No | Italian | (Lattante et al., 2012) |
1 patient | — | — | — | Yesa | — | Yes | Chinese | (Soong et al., 2014) |
1 patient | M | 65 | S | Yesb | 36 | Yes | French | (Caroppo et al., 2016) |
2 patients | F | 38 | LL | No | >24 | Yes | Chinese | (Cheng et al., 2016) |
F | 62 | B | Yesc | >60 | Yes | Chinese | ||
1 patient | M | 52 | S | Nod | >36 | Yes | Spanish | (González‐Sánchez et al., 2018) |
1 patient | F | 45 | UL | No | 36 | No | Chinese | (Wang et al., 2020) |
Patient 2 | F | 53 | B | No | 23 | No | Chinese | This study |
Patient 3 | M | 57 | LL | Yes | >61 | No | Chinese | This study |
No detailed description of FTD.
Onset of behavioral variant of FTD (bvFTD) at age 65 then ALS at age 67.
She presented bvFTD 2.5 years later.
His older sister with p.I383V mutation showed semantic variant primary progressive aphasia (svPPA).
Abbreviations: — = absent; AOO = age of onset; B = bulbar; FTD = frontotemporal dementia; LL = lower limb; S = spinal; SOO = site of onset; UL = upper limb.