FIGURE 4.

LiOr as a replacement for Li₂CO₃ in the treatment of BD. Proponents of LiOr argue that LiOr can cross biological membranes and enter cells more readily than Li₂CO₃, allowing for lesser concentrations to be administered while maintaining an equivalent therapeutic effect. While LiOr has been found to result in higher brain concentrations of lithium than Li₂CO₃, others have noted that this may come at the cost of increased renal toxicity. More research into both benefits (e.g., increased accumulation within cells) and drawbacks (e.g., renal toxicity) is needed