FIGURE 3.

miR‐485‐5p overexpression decreased the epileptic‐discharges of DRE rats. (a) The numbers of seizures (grade ≥ 4) in 12 h/d*7 were significantly decreased by the AAV‐miR‐485‐5p infection at 14 weeks after SE (n = 4, p < .05). (b and c) miR‐485‐5p overexpression decreased the epileptic‐discharges of hippocampal neurons of rats with DRE. (b) Samples of whole cell current recording using hippocampal slices of DRE rats. (c) Barographs of the numbers of epileptiform spikes in hippocampal slices of DRE rats (15 neurons were recorded from three rats for each group). * p < .05