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. 2021 Aug 13;15:730417. doi: 10.3389/fnins.2021.730417

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Copyright © 2021 Verdinez and Sebag.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Role of N-glycosylation in PKR2 signaling. (A–D) Inositol phosphate detection in cells expressing PKR2 (A), PKR2-N7Q (B), PKR2-N27Q (C), or PKR2-N7/27Q (D) with or without MRAP2 and stimulated with the indicated concentration of PK2. (E–H) cAMP measurement in cells expressing PKR2 (E), PKR2-N7Q (F), PKR2-N27Q (G), or PKR2-N7/27Q (H) with or without MRAP2 and stimulated with the indicated concentration of PK2. Errors are mean ± SEM. **p < 0.01, ***p < 0.001.