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. 2021 Aug 13;12:691605. doi: 10.3389/fimmu.2021.691605

Table 2.

Comparison of adverse reactions between peptide therapy and chemotherapy in treated patients.

Adverse Effects Any grade Grades 3 to 4
Chemotherapy Neoantigen vaccine Chemotherapy Neoantigen vaccine
N (%) N (%) N (%) N (%)
Gastrointestinal reaction 7 (100.0) 0 (0.0) 2 (28.6) 0 (0.0)
Thrombocytopenia 5 (71.4) 0 (0.0) 2 (28.6) 0 (0.0)
Rash 2 (28.6) 1 (14.3) 0 (0.0) 0 (0.0)
Fever 1 (14.3) 0 (0.0) 0 (0.0) 0 (0.0)
Neutropenia 7 (100.0) 0 (0.0) 4 (57.1) 0 (0.0)
Peripheral nerve abnormalities 3 (42.9) 0 (0.0) 0 (0.0) 0 (0.0)
Anemia 5 (71.4) 0 (0.0) 1 (14.3) 0 (0.0)
Elevated transaminase 3 (42.9) 0 (0.0) 0 (0.0) 0 (0.0)
Fatigue 7 (100.0) 0 (0.0) 1 (14.3) 0 (0.0)